Clinical trial design is the process of planning and organizing a clinical trial to test the safety and effectiveness of a new medical intervention, such as a drug, medical device, or treatment approach. This includes determining the study population, defining the research question and objectives, selecting appropriate outcome measures, determining the study design (e.g. randomized controlled trial, observational study), and establishing the study protocol. Key considerations in clinical trial design include sample size, randomization, blinding, control group selection, and endpoint selection. The goal of a well-designed clinical trial is to minimize bias and ensure the validity and reliability of the study results, ultimately providing valuable evidence to inform clinical practice and healthcare decision-making.